![]() Sixteen participants with 2020 onset had >1 year follow up, with the latest onset on 1/19/21. Some patients were initially evaluated early in the course and others later, and investigations continued for months. 4, 5 Participants 9 and 15 had distal muscle weakness and atrophy. ![]() Initial neuromuscular examinations ( Table 3) averaged 77.0% of ideal, with reduced/abnormal distal pin and vibration sensations and absent Achilles reflexes most prevalent. 2 Initial SFN symptom scores ( Table 2) were abnormal-reduced to 40.7% of ideal on average-with pain scores averaging 4.8/10. ![]() ![]() Diagnostic tests for neuropathy ( Table 1) revealed that 16.7% electrodiagnostic studies were abnormal, whereas 62.5% (10/16) of lower leg skin biopsies pathologically confirmed SFN, as corroborated by 50% of upper thigh biopsies and autonomic function tests. Participants' ages averaged 43.3 ± 3.3 years on COVID D1, and 68.8% were female 18.8% were Latino, and 94.1% were Caucasian. ![]()
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